Univariate analysis showed that gender, age, lesion location, T stage, and perineural invasion/lymphvascular invasion (PNI/PVI) had no significant effect on cervical lymph node metastasis ( P>0.05). The number of positive lymph node metastases in the corresponding levels were 2, 17, 17, 1, 5, 0, and 0 respectively. The level number of positive areas in the IA, IB, IIA, IIB, III, IV and V levels was 2, 15, 12, 1, 4,0, and 0, respectively. A total of 42 positive lymph nodes were detected in 34 cervical levels. Among them, there were 28 cases of lymph node metastasis in one cervical level and 3 cases in two cervical levels. Results: Thirty-one out of 161 cases (19%) were confirmed cervical lymph node metastasis. The risk factors of cervical lymph node metastasis in patients were analyzed by univariate and multivariate Logistic regression analysis. The level and number of cervical lymph node metastasis were confirmed by postoperative pathology.

All patients underwent extended primary resection combined with cervical lymph node dissection. Methods: The clinical data of 161 OSCC patients with cN0 were retrospectively analyzed. Objective: To explore the risk factors of cervical lymph node metastasis in oral squamous cell carcinoma (OSCC) patients with clinical negative cervical lymph nodes(cN0) and provide a reference for clinical treatment. Select the file that you have just downloaded and select import option Reference Manager (RIS). Risk Factors Analysis of Pathologically Confirmed Cervical Lymph Nodes Metastasis in Oral Squamous Cell Carcinoma Patients with Clinically Negative Cervical Lymph Node: Results from a Cancer Center of Central China. Li Y, Liu K, Ke Y, Zeng Y, Chen M, Li W, Liu W, Hua X, Li Z, Zhong Y, Xie C, Yu H.

✉ Corresponding author: Haijun Yu, Mailing address: Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, 169 Donghu Road, Wuhan 430000, China. *Yonghong Li and Ke Liu contributed equally to this work Department of Oromaxillofacial and Head Neck Oncology, School and Hospital of Stomatology, Wuhan University, Wuhan, China Department of Oncology and Surgery, The First Hospital of Tianmen City of Hubei Province, Tianmen, Hubei, Chinaģ. Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University Hubei Cancer Clinical Study Center, Hubei Key Laboratory of Tumor Biological Behaviors, Wuhan, ChinaĢ. Yonghong Li 1,2*, Ke Liu 3*, Yuan Ke 1, Yifei Zeng 1, Mengge Chen 1, Wei Li 2, Wenming Liu 2, Xinying Hua 1, Zheng Li 1, Yahua Zhong 1, Conghua Xie 1, Haijun Yu 1ġ. Research Paper Risk Factors Analysis of Pathologically Confirmed Cervical Lymph Nodes Metastasis in Oral Squamous Cell Carcinoma Patients with Clinically Negative Cervical Lymph Node: Results from a Cancer Center of Central China

Pathological lymph node